The essential amino acid L-tryptophan (Trp) is used as a pharmaceutical agent, especially in neuro-medicine. It is also added into feed products as a food fortifier. Furthermore, application of Trp is widespread in biotechnology. Tryptophan is an amino acid necessary for growth in infants and for nitrogen balance in adults. Trp is produced by a condensation reaction between indole and L-serine, which is catalyzed by bacterial tryptophanase activity. In this review, we investigate Trp production using microbial system in the presence and absence of its precursors. In the present review on the production of tryptophan by using E.coli bacteria and many types, Fermentation condition and some application use in industries etc.
Loading....